Article
Alu-repeat polymorphism in the gene coding for tissue-type plasminogen activator (t-PA) and risks of myocardial infarction among middle-aged men.
Arteriosclerosis, thrombosis, and vascular biology - 1 Sept 1997
Ridker P M, Baker M T, Hennekens C H, Stampfer M J, Vaughan D E
Abstract excerpt
An Alu-repeat polymorphism in the gene coding for tissue-type plasminogen activator has been described recently, and it has been hypothesized that this polymorphism may predict risk of coronary thrombosis. In a prospective cohort of nearly 15,000 apparently healthy men, presence of an Alu-repeat...
Topics
- Aging
- Alleles
- Cohort Studies
- DNA Transposable Elements
- Gene Deletion
- Gene Frequency
- Genotype
- Humans
- Male
- Middle Aged
- Multivariate Analysis
- Myocardial Infarction
- Polymorphism, Genetic
- Prospective Studies
- Repetitive Sequences, Nucleic Acid
- Risk Factors
- Smoking
- Tissue Plasminogen Activator