Article
Association study of schizophrenia and the histidase gene.
Psychiatric genetics - 1 Jan 1997
Nobile M, Maffei P, Nöthen M M, Rietschel M, Smeraldi E, Catalano M
Abstract excerpt
Previous findings of increased heterozygosity for histidinemia among schizophrenic patients make the histidase gene a plausible candidate for genetic studies in schizophrenia. In the present study, we used a tetranucleotide repeat polymorphism in intron 8 of the histidase gene to examine the possibility that the histidase gene contributes to the genetic component of schizophrenia. In a first sample of 161...
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