Article
Dopamine-adenosine interactions in the striatum and the globus pallidus: inhibition of striatopallidal neurons through either D2 or A2A receptors enhances D1 receptor-mediated effects on c-fos expression.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 15 Oct 1997
Le Moine C, Svenningsson P, Fredholm B B, Bloch B
Abstract excerpt
D1 receptors located on striatonigral neurons and D2 receptors located, together with A2A receptors, on striatopallidal neurons are known to interact functionally. Using in situ hybridization, we examined the effects of D1 and D2 agonists and of an A2A antagonist on c-fos mRNA in identified stria...
Topics
- Adenosine
- Animals
- Caudate Nucleus
- Corpus Striatum
- Dopamine
- Dopamine Agonists
- Drug Combinations
- Globus Pallidus
- Male
- Neural Inhibition
- Neurons
- Phenotype
- Proto-Oncogene Proteins c-fos
- Purinergic P1 Receptor Agonists