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Epidermal barrier in disorders of the skin

15 Aug 1997

Abstract excerpt

The water permeability barrier of the stratum corneum (SC) seems primarily to be regulated by the lamellarly arranged lipid bilayers between the corneocytes, which originate largely from polar lipid precursors provided by the cells of stratum granulosum via exocytosis of the lamellar body (LB) content. In particular, the structural organization of these intercellular lipid lamellae seems to be responsible for the...

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PMID: 9297686
DOI: 10.1002/(sici)1097-0029(19970815)38:4<361::aid-jemt4>3.0.co;2-m

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