Article
The effect of lead exposure and serum deprivation on mesencephalic primary cultures.
Neurotoxicology - 1 Jan 1997
Scortegagna M, Hanbauer I
Abstract excerpt
The effect of Pb2+ was studied in embryonic mesencephalic primary cultures that contain neurons and glia. Pb2+ exposure in absence of serum, damaged more efficaciously the cultured cells than Pb2+ exposure in presence of serum. In serum-free medium, Pb2+ elicited mainly necrosis and apoptosis in maximally 13% of the cells in culture. The glial fibrillary acidic protein (GFAP) content was decreased by Pb2+...
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