Article
Replicative potential and telomere length in human skeletal muscle: implications for satellite cell-mediated gene therapy.
Human gene therapy - 10 Aug 1997
Decary S, Mouly V, Hamida C B, Sautet A, Barbet J P, Butler-Browne G S
Abstract excerpt
In this study, we have evaluated the ability of human satellite cells isolated from subjects aged from 5 days to 86 years to proliferate in culture. Cells were cultivated until they became senescent. The number of cell divisions was calculated by counting the number of cells plated in culture compared to the number of cells removed following proliferation. Telomere length, which is known to decrease during each...
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