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Insulin-Like Growth Factor I in the Teleost Oreochromis mossambicus, the Tilapia: Gene Sequence, Tissue Expression, and Cellular Localization*

1 Sept 1997

Abstract excerpt

Using reverse transcription-PCR and molecular cloning, the complementary DNA sequence encoding preproinsulin-like growth factor I (IGF-I) of a teleost, the tilapia (Oreochromis mossambicus) was established from liver. At the amino acid level, tilapia IGF-I shows all residues necessary for the maintenance of tertiary structure and shares about 80% identity with IGF-I from other teleosts. The B and A domains of...

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PMID: 9275043
DOI: 10.1210/endo.138.9.5375

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