Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Stage-specific expression of a selectable marker in Toxoplasma gondii permits selective inhibition of either tachyzoites or bradyzoites.

Molecular and biochemical parasitology - 1 Sept 1997

Bohne W, Roos D S

Abstract excerpt

The establishment of culture conditions suitable for inducing differentiation of Toxoplasma gondii tachyzoites into parasites resembling the latent bradyzoite form has opened this important developmental transition to experimental analysis. In order to develop a genetic marker suitable for positive and negative selection during parasite differentiation. the T. gondii HXGPRT gene was placed under control of 5'...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to DNA Primers
Share to Genes, Helminth

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Markers

Share to Hypoxanthine Phosphoribosyltransferase

Share to Mutation

Share to Polymerase Chain Reaction

Share to Promoter Regions, Genetic

Source

Identifiers

PMID: 9274873
DOI: 10.1016/s0166-6851(97)00087-x

Genes

UPRT
BAG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Stage-specific expression of a selectable marker in Toxoplasma gondii permits selective inhibition of either tachyzoites or bradyzoites.PMID 9274873Read ↗

Identification and characterization of differentiation mutants in the protozoan parasite Toxoplasma gondii.Semantic proximity Read ↗

Isolation of Developmentally Regulated Genes from Toxoplasma gondii by a Gene Trap with the Positive and Negative Selectable Marker Hypoxanthine-Xanthine-Guanine PhosphoribosyltransferaseSemantic proximity Read ↗

Gene knock-outs and allelic replacements in Toxoplasma gondii: HXGPRT as a selectable marker for hit-and-run mutagenesis.Semantic proximity Read ↗

Genetic analysis of tachyzoite to bradyzoite differentiation mutants in Toxoplasma gondii reveals a hierarchy of gene induction.Semantic proximity Read ↗

Constitutive upregulation of transcription factors underlies permissive bradyzoite differentiation in a natural isolate of <i>Toxoplasma gondii</i>Semantic proximity Read ↗

Understanding mechanisms and the role of differentiation in pathogenesis of Toxoplasma gondii: a reviewSemantic proximity Read ↗

The transcriptome of Toxoplasma gondii.Semantic proximity Read ↗

The transcription of bradyzoite genes in <i>Toxoplasma gondii</i> is controlled by autonomous promoter elementsSemantic proximity Read ↗

Tagging Genes and Trapping Promoters inToxoplasma gondiiby Insertional MutagenesisSemantic proximity Read ↗

GCN5a is a telomeric lysine acetyltransferase whose loss primes <i>Toxoplasma gondii</i> for latencySemantic proximity Read ↗

Dynamics of Toxoplasma gondii DifferentiationSemantic proximity Read ↗

Expansion of experimental genetics approaches for Plasmodium berghei with versatile transfection vectors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.