Article
Changes in phenotypes of apolipoprotein E and apolipoprotein(a) in liver transplant recipients.
Clinical transplantation - 1 Aug 1997
Fernández-Miranda C, Cancelas P, de la Calle A, Gómez R, Moreno E, Gómez-Gerique J, del Palacio A
Abstract excerpt
The aim of this study has been to confirm that liver is the main site of apolipoprotein (apo) E and apo(a) synthesis, based in the changes of their phenotypes after transplantation. Apo E phenotypes were studied in 34 patients and apo(a) phenotypes in 27 of them before and after liver transplant. Thirteen patients changed the apo E phenotype after transplantation. Eight patients with E3/3 phenotype changed to the...
Topics
- Alleles
- Apolipoprotein E2
- Apolipoprotein E3
- Apolipoprotein E4
- Apolipoproteins E
- Electrophoresis, Polyacrylamide Gel
- Enzyme-Linked Immunosorbent Assay
- Female
- Hepatitis
- Humans
- Lipoprotein(a)
- Liver
- Liver Cirrhosis
- Liver Cirrhosis, Alcoholic
- Liver Transplantation
- Male
- Middle Aged
- Phenotype