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Article

Clonal HTLV-I-infected CD4+ T-lymphocytes and non-clonal non-HTLV-I-infected giant cells in incipient ATLL with Hodgkin-like histologic features.

International journal of cancer - 7 Aug 1997

Ohshima K, Suzumiya J, Kato A, Tashiro K, Kikuchi M

Abstract excerpt

Lymph nodes from the incipient or early neoplastic phase of adult T-cell leukemia/lymphoma (ATLL) histologically resemble Hodgkin's disease. Integrated proviral human T-lymphotrophic virus type I (HTLV-I) has been demonstrated in such lesions. We studied 18 patients with this disease, and about half of the cases developed typical ATLL within 2 or 3 years. In all cases, either mono- or oligoclonal cell populations...

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Identifiers

PMID: 9259396
DOI: 10.1002/(sici)1097-0215(19970807)72:4<592::aid-ijc7>3.0.co;2-l

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