Article
Clonal HTLV-I-infected CD4+ T-lymphocytes and non-clonal non-HTLV-I-infected giant cells in incipient ATLL with Hodgkin-like histologic features.
International journal of cancer - 7 Aug 1997
Ohshima K, Suzumiya J, Kato A, Tashiro K, Kikuchi M
Abstract excerpt
Lymph nodes from the incipient or early neoplastic phase of adult T-cell leukemia/lymphoma (ATLL) histologically resemble Hodgkin's disease. Integrated proviral human T-lymphotrophic virus type I (HTLV-I) has been demonstrated in such lesions. We studied 18 patients with this disease, and about h...
Topics
- Adolescent
- Adult
- Aged
- Blotting, Southern
- CD4-Positive T-Lymphocytes
- Child
- Child, Preschool
- Clone Cells
- DNA, Viral
- DNA-Binding Proteins
- Female
- Gene Expression
- Genes, Immunoglobulin
- Genome, Viral
- Genotype
- Giant Cells
- HTLV-I Infections
- Herpesvirus 4, Human