Article
Cloning of a Chinese hamster ovary (CHO) cDNA encoding phosphatidylserine synthase (PSS) II, overexpression of which suppresses the phosphatidylserine biosynthetic defect of a PSS I-lacking mutant of CHO-K1 cells.
The Journal of biological chemistry - 1 Aug 1997
Kuge O, Saito K, Nishijima M
Abstract excerpt
Phosphatidylserine (PtdSer) in mammalian cells is synthesized through the exchange of free L-serine for the polar head group (base) of preexisting phospholipid. We previously showed the presence of two different enzymes catalyzing the serine base exchange in Chinese hamster ovary (CHO) cells and...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- CHO Cells
- Cloning, Molecular
- Cricetinae
- Molecular Sequence Data
- Mutation
- Nitrogenous Group Transferases
- Phosphatidylcholines
- Phosphatidylethanolamines
- Phosphatidylserines
- Transfection
- Transferases