Article
Pathogenesis of Tourette's syndrome.
Journal of child psychology and psychiatry, and allied disciplines - 1 Jan 1997
Leckman J F, Peterson B S, Anderson G M, Arnsten A F, Pauls D L, Cohen D J
Abstract excerpt
This review presents a models of disease pathogenesis in the context of CNS development. It begins with an exploration of the clinical features and natural history of Tourette's syndrome. This is followed by a consideration of the role of genetic and nongenetic factors. An effort is then made to review the anatomical organization of the basal ganglia and related cortical sites. These circuits are intimately...
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