Localization of somatostatin receptor genes on mouse chromosomes 2, 11, 12, 15, and 17: correlation with growth QTLs.

doi:10.1006/geno.1997.4781

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Article

Localization of somatostatin receptor genes on mouse chromosomes 2, 11, 12, 15, and 17: correlation with growth QTLs.

Genomics - 1 Jul 1997

Brinkmeier M L, Camper S A

Abstract excerpt

A major role of the peptide hormone somatostatin is inhibition of growth hormone secretion. The effects of somatostatin are mediated through five distinct G-protein-coupled receptors, each of which is expressed in the pituitary gland and other tissues. Allelic variation in the five somatostatin receptor genes (Smstr) could contribute to growth rate and overall body size. To evaluate this hypothesis we determined...

Topics

Alleles
Animals
Base Sequence
Chromosome Mapping
Crosses, Genetic
DNA Primers
Female
Genetic Variation
Growth
Male
Mice
Mice, Inbred C57BL

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Muridae

Mutation

Polymerase Chain Reaction

Polymorphism, Restriction Fragment Length

Receptors, Somatostatin

Source

Open in PubMed

Identifiers

PMID: 9226367
DOI: 10.1006/geno.1997.4781

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