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Article

Molecular identification of a novel retrovirus repeatedly isolated from patients with multiple sclerosis

8 Jul 1997

Abstract excerpt

The partial molecular characterization of multiple sclerosis (MS)-associated retrovirus (MSRV), a novel retrovirus previously called LM7, is reported. MSRV has been isolated repeatedly from leptomeningeal, choroid plexus and from Epstein-Barr virus-immortalized B cells of MS patients. A strategy based on reverse transcriptase PCR with RNA-purified extracellular virions yielded an initial pol fragment from which...

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PMID: 9207135
DOI: 10.1073/pnas.94.14.7583

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