Frequency of Smad gene mutations in human cancers.

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Article

Frequency of Smad gene mutations in human cancers.

Cancer research - 1 Jul 1997

Riggins G J, Kinzler K W, Vogelstein B, Thiagalingam S

Abstract excerpt

Much excitement has recently been generated by the discovery of the Smad genes, encoding proteins that transduce signals from the transforming growth factor beta family of cytokines. Here, we report the completion of cloning of the six known human Smads, providing novel sequences for Smad5 and Sm...

Topics

Amino Acid Sequence
Brain Neoplasms
Breast Neoplasms
Colorectal Neoplasms
DNA-Binding Proteins
Esophageal Neoplasms
Female
Genes, Tumor Suppressor
Head and Neck Neoplasms
Humans
Lung Neoplasms
Male
Molecular Sequence Data
Mutation
Neoplasms
Ovarian Neoplasms
Pancreatic Neoplasms
Phosphoproteins

Source

Open in PubMed

Identifiers

PMID: 9205057

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9205057-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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