Article
Organization of the human LU gene and molecular basis of the Lu(a)/Lu(b) blood group polymorphism.
Blood - 15 Jun 1997
El Nemer W, Rahuel C, Colin Y, Gane P, Cartron J P, Le Van Kim C
Abstract excerpt
The Lutheran (Lu) blood group antigens and the B-cell adhesion molecule (B-CAM) epithelial cancer antigen are carried by recently cloned integral glycoproteins that belong to the Ig superfamily. We have previously shown that the Lu and B-CAM antigens are encoded by the same gene, LU, and that alternative splicing of the primary transcript most likely accounts for the presence of both antigens on two isoforms that...
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