Article
Correlation of functional domains and rates of nucleotide substitution in cytochrome b.
Molecular phylogenetics and evolution - 1 Jun 1997
Griffiths C S
Abstract excerpt
Distinguishing noise from signal presents a problem when DNA sequences are used for phylogeny reconstruction. Multiple substitutions at sites are a primary cause of noise and this is compounded by variation in substitution rates among sites. For protein-coding genes, one method used to determine if data are noisy is to assess levels of saturation of substitutions by codon position. However, this procedure may not...
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