Article
Functional, morphological, and phenotypical differences between rat alveolar and interstitial macrophages.
American journal of respiratory cell and molecular biology - 1 May 1997
Johansson A, Lundborg M, Sköld C M, Lundahl J, Tornling G, Eklund A, Camner P
Abstract excerpt
Alveolar macrophages (AM) and interstitial macrophages (IM) from rat lungs were characterized with respect to morphology, phagocytosis, adhesion properties, and phenotype. AM were recovered by lung lavage and IM by treatment of the lung tissue with DNAse and collagenase. The AM were enzyme treated in the same way as the IM. The IM were smaller than AM and had a higher nuclear to cytoplasm ratio. They had markedly...
Topics
- Animals
- Antigens, Surface
- Cell Adhesion
- Cells, Cultured
- Fibronectins
- Hydrogen-Ion Concentration
- Lung
- Macrophages
- Macrophages, Alveolar
- Male
- Phagocytosis
- Phagosomes
- Phenotype
- Rats
- Rats, Sprague-Dawley
- Vitronectin
