Article
TaqI polymorphism in the 3' flanking region of the PI gene among Kuwaiti Arabs and Russians.
Disease markers - 1 Apr 1997
Samilchuk E, D'Souza B, Voevodin A, Chuchalin A, al-Awadi S
Abstract excerpt
The Taq1 polymorphism in the 3' flanking region of the PI gene has been reported to be associated with chronic obstructive pulmonary disease (COPD). We have studied the frequency of the Taq1 polymorphism in 117 Kuwaiti Arabs and 110 Russians using PCR/RFLP. The frequency of this polymorphism was found to be 0.235 in the Arabs and 0.027 in the Russians. Such a striking difference in allele frequencies could be due...
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