Article
Simultaneous detection and strain differentiation of Mycobacterium tuberculosis for diagnosis and epidemiology
1 Apr 1997
Abstract excerpt
Widespread use of DNA restriction fragment length polymorphism (RFLP) to differentiate strains of Mycobacterium tuberculosis to monitor the transmission of tuberculosis has been hampered by the need to culture this slow-growing organism and by the level of technical sophistication needed for RFLP typing. We have developed a simple method which allows simultaneous detection and typing of M. tuberculosis in...
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