Population variation at the polymorphic ApaLI restriction enzyme site in intron 5 of the WT1 gene.

doi:10.1111/j.1399-0004.1996.tb02738.x

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Population variation at the polymorphic ApaLI restriction enzyme site in intron 5 of the WT1 gene.

Clinical genetics - 1 Dec 1996

Besnard-Guérin C, Winqvist R, Newsham I, Cavenee W K

Abstract excerpt

We examined 63 unrelated individuals from the United States for the Apa-LI polymorphism in intron 5 of the WT1 gene. Allele frequencies of 0.13 and 0.87 for the A and B alleles, respectively, and a heterozygosity index of 24% contrast sharply with previous data obtained in the Japanese population where allele frequencies of 0.55 and 0.45 for the A and B alleles and a heterozygosity index of 59% were reported....

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Population variation at the polymorphic ApaLI restriction enzyme site in intron 5 of the WT1 gene.

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