Article
A history of miscarriages and mild prognathism as possible mode of presentation of mosaic trisomy 18 in women.
Clinical genetics - 1 Dec 1996
Satge D, Geneix A, Goburdhun J, Lasne-Desmet P, Rosenthal C, Arnaud R, Malet P
Abstract excerpt
A 22-year-old woman seeking medical assistance for hypofertility after two miscarriages had very slight anomalies: mild macrogenia and prognathism, and temporal depilation. Peripheral lymphocytes and fibroblastic karyotypes disclosed the tenth published case of low-level mosaicism for trisomy 18 with normal intelligence. Subfertility is frequently observed among these patients. As women with this anomaly are at...
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