Article
Immunostimulation in the urinary bladder by local application of Nocardia rubra cell wall skeleton preparation (Rubratin) for superficial bladder cancer immunotherapy--a phase I/II study.
Urological research - 1 Jan 1997
de Reijke T M, de Boer E C, Schamhart D H, Kurth K H
Abstract excerpt
OBJECTIVES: Twelve patients with superficial papillary transitional cell carcinoma of the bladder (pTa, pT1) were treated with six consecutive weekly intravesical instillations of Rubratin (in a dose of 1.5, 3.0, or 4.5 mg), a cell wall skeleton preparation of Nocardia rubra (NCW). The main objec...
Topics
- BCG Vaccine
- Carcinoma, Transitional Cell
- Cell Separation
- Cell Wall
- Cytokines
- Female
- Flow Cytometry
- Humans
- Immunotherapy
- Leukocytes
- Male
- Nocardia
- Phenotype
- Urinary Bladder Neoplasms
- Urine