Article
Cell mediated immunity induced in mice by HPV 16 L1 virus-like particles.
Microbial pathogenesis - 1 Apr 1997
Dupuy C, Buzoni-Gatel D, Touze A, Le Cann P, Bout D, Coursaget P
Abstract excerpt
Recombinant human papillomavirus (HPV) type 16 L1 virus-like particles (VLPs) expressed in the baculovirus system were used to investigate the cellular immune response to human papillomavirus type 16. The cell-mediated immune response was evaluated through immunization of mice with HPV 16 L1 virus-like particles using a lymphoproliferation assay and cytokine production and cytometric analysis of lymphocyte...
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