Article
Isolated maxillary bending in CL/FR strain mice: observation of craniofacial deformity and inheritance pattern.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association - 1 Mar 1997
Nagata M, Amin N, Kannari Y, Hayatsu M, Ohashi Y, Oguro A
Abstract excerpt
OBJECTIVE: The CL/Fr mouse, known as a strain with spontaneous cleft lip and/or palate (CL/P), has been used as an animal model to investigate etiology in CL/P. METHOD: We examined a facial asymmetry mutant discovered in a CL/Fr mouse colony that was not associated with CL/P and was shown to be i...
Topics
- Animals
- Branchial Region
- Cephalometry
- Cleft Lip
- Cleft Palate
- Crosses, Genetic
- Disease Models, Animal
- Facial Asymmetry
- Female
- Gene Expression
- Genes, Recessive
- Genome
- Inbreeding
- Male
- Maxilla
- Maxillofacial Development
- Mice
- Mice, Inbred C57BL