Article
Isolated maxillary bending in CL/FR strain mice: observation of craniofacial deformity and inheritance pattern.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association - 1 Mar 1997
Nagata M, Amin N, Kannari Y, Hayatsu M, Ohashi Y, Oguro A
Abstract excerpt
OBJECTIVE: The CL/Fr mouse, known as a strain with spontaneous cleft lip and/or palate (CL/P), has been used as an animal model to investigate etiology in CL/P. METHOD: We examined a facial asymmetry mutant discovered in a CL/Fr mouse colony that was not associated with CL/P and was shown to be inheritable in subsequent generations. Facial asymmetry became apparent with postnatal growth, whereas it was not...
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