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Article

Dwarfism in Dexter cattle is not caused by the mutations in FGFR3 responsible for achondroplasia in humans.

Animal genetics - 1 Feb 1997

Usha A P, Lester D H, Williams J L

Abstract excerpt

Dexter cattle carry a genetic defect causing a dwarf phenotype in the heterozygotes (Dx+/-), while homozygotes (Dx+/+) are stillborn with extreme shortening of limbs and gross craniofacial defects and are described as 'bulldog' calves. The heterozygous phenotype has been likened to achondroplastic dwarfism in humans (ACH), which has recently been shown to be the result of mutations in the transmembrane region of...

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Source

Identifiers

PMID: 9124710
DOI: 10.1111/j.1365-2052.1997.00068.x

Genes

FGFR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Dwarfism in Dexter cattle is not caused by the mutations in FGFR3 responsible for achondroplasia in humans.PMID 9124710Read ↗

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Achondroplastic dog breeds have no mutations in the transmembrane domain of the FGFR-3 gene.Semantic proximity Read ↗

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Mutations in the transmembrane domain of FGFR3 cause the most common genetic form of dwarfism, achondroplasia.Semantic proximity Read ↗

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