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Article

Achondroplastic dog breeds have no mutations in the transmembrane domain of the FGFR-3 gene.

Canadian journal of veterinary research = Revue canadienne de recherche veterinaire - 1 Oct 2000

Martínez S, Valdés J, Alonso R A

Abstract excerpt

One of the most common skeletal affections in humans is achondroplasia, a short-limbed dwarfism that is, in most cases, caused by mutations in the transmembrane domain of the fibroblast growth factor receptor-3 (FGFR-3) gene. Due to the lack of sufficient radiological, genetic, and molecular studies, most types of skeletal anomalies in dogs are classified as achondroplasia. To initiate the molecular...

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PMID: 11041504
PMCID: PMC1189626

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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