Article
Clinical and molecular characteristics of a Brazilian family with spinocerebellar ataxia type 1.
Arquivos de neuro-psiquiatria - 1 Sept 1996
Lopes-Cendes I, Steiner C E, Silveira I, Pinto Júnior W, Maciel J A, Rouleau G A
Abstract excerpt
The spinocerebellar ataxias (SCAs) are a clinically and genetically heterogeneous group of late onset neurodegenerative disorders. To date, seven different genes causing autosomal dominant SCA have been mapped: SCA1, SCA2, Machado-Joseph disease (MJD)SCA3, SCA4, SCA5, SCA7 and dentatorubropallido...
Topics
- Adult
- Brazil
- Female
- Genetic Counseling
- Genetic Heterogeneity
- Humans
- Male
- Middle Aged
- Mutation
- Pedigree
- Spinocerebellar Degenerations