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Chromosome 17 and hereditary dementia

1 Apr 1997

Abstract excerpt

Several previous families with differing clinical and pathologic characteristics have demonstrated linkage to the 17q21-22 region. We have performed a linkage analysis with chromosome 17 markers on three families showing autosomal dominant inheritance of non-Alzheimer dementia and 60 kindreds with late-onset familial Alzheimer's disease (FAD). Family A shows unequivocal evidence of linkage with a maximum lod...

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PMID: 9109883
DOI: 10.1212/wnl.48.4.949

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