Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cooperative and non-cooperative DNA binding modes of catabolite control protein CcpA from Bacillus megaterium result from sensing two different signals.

Journal of molecular biology - 7 Mar 1997

Gösseringer R, Küster E, Galinier A, Deutscher J, Hillen W

Abstract excerpt

Carbon catabolite repression (CCR) of several operons in Bacillus subtilis and Bacillus megaterium is mediated by the cis-acting cre sequence and trans-acting catabolite control protein (CcpA). We describe purification of CcpA from B. megaterium and its interaction with regulatory sequences from the xyl operon. Specific interaction of CcpA with cre as scored by DNase I footprints at concentrations similar to the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Proteins
Share to DNA, Bacterial

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA-Binding Proteins

Share to Electrophoresis, Polyacrylamide Gel

Share to Gene Expression Regulation, Bacterial

Share to Genes, Bacterial

Share to Mutation

Share to Phosphorylation

Source

Identifiers

PMID: 9102460
DOI: 10.1006/jmbi.1996.0820

Genes

PTS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cooperative and non-cooperative DNA binding modes of catabolite control protein CcpA from Bacillus megaterium result from sensing two different signals.PMID 9102460Read ↗

Structural mechanism for the fine-tuning of CcpA function by the small molecule effectors glucose 6-phosphate and fructose 1,6-bisphosphate.Semantic proximity Read ↗

Transcriptome analysis of temporal regulation of carbon metabolism by CcpA in Bacillus subtilis reveals additional target genes.Semantic proximity Read ↗

PRD-Containing Virulence Regulators (PCVRs) in Pathogenic BacteriaSemantic proximity Read ↗

The X-ray crystal structures of two constitutively active mutants of the Escherichia coli PhoB receiver domain give insights into activation.Semantic proximity Read ↗

The Bacillus subtilis crh gene encodes a HPr-like protein involved in carbon catabolite repression.Semantic proximity Read ↗

Genome‐wide analysis of in vivo CcpA binding with and without its key co‐factor HPr in the major human pathogen group A StreptococcusSemantic proximity Read ↗

The Bacillus subtilis mannose regulator, ManR, a DNA-binding protein regulated by HPr and its cognate PTS transporter ManP.Semantic proximity Read ↗

Connecting two-component regulatory systems by a protein that protects a response regulator from dephosphorylation by its cognate sensor.Semantic proximity Read ↗

Control of the phosphorylation state of the HPr protein of the phosphotransferase system in Bacillus subtilis: implication of the protein phosphatase PrpC.Semantic proximity Read ↗

The Catabolite Control Protein CcpA Binds to P mga and Influences Expression of the Virulence Regulator Mga in the Group A StreptococcusSemantic proximity Read ↗

Cross communication between components of carbon catabolite repression of Lactobacillus casei and Bacillus megaterium.Semantic proximity Read ↗

Multiple phosphorylation of SacY, a Bacillus subtilis transcriptional antiterminator negatively controlled by the phosphotransferase system.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.