Article
Analysis of expression of an alternative La (SS-B) cDNA and localization of the encoded N- and C-terminal peptides.
Biochimica et biophysica acta - 27 Mar 1997
Bachmann M, Grölz D, Bartsch H, Klein R R, Tröster H
Abstract excerpt
A deletion of an (A)-residue was detected in a cDNA encoding for the nuclear autoantigen La/SS-B. The cDNA was recently isolated from a cDNA library made from peripheral blood lymphocytes of a patient with primary Sjögren's Syndrome. The region, where the deletion occurred, represents a hot spot...
Topics
- Amino Acid Sequence
- Autoantigens
- Baculoviridae
- Base Sequence
- Cell Line
- DNA, Complementary
- Escherichia coli
- Gene Deletion
- Humans
- Molecular Sequence Data
- Mutation
- Peptide Fragments
- Ribonucleoproteins
- Sjogren's Syndrome
- SS-B Antigen