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Article

DQB10202 and the new DQB10203 allele: a fourth pair of DQB1 alleles differing only at codon 57.

Tissue antigens - 1 Mar 1997

Olerup O, Aldener-Cannavá A, Fogdell-Hahn A, Getty R R, Wagenknecht D R, McIntyre J A

Abstract excerpt

Amino acid 57 of DQ beta chains is of functional importance as it influences peptide binding, is part of B and T cell epitopes, and is associated with susceptibility and resistance to insulin-dependent diabetes mellitus and humoral immunodeficiencies. Polymorphism of codon 57 is conserved in primates and in HLA class II B genes implying that balancing selection operates on this residue. Previously, three DQB1...

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Identifiers

PMID: 9098936
DOI: 10.1111/j.1399-0039.1997.tb02750.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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