Article
Effect of the growth rate of Pseudomonas aeruginosa biofilms on the susceptibility to antimicrobial agents.
Chemotherapy - 1 Jan 2000
Shigeta M, Komatsuzawa H, Sugai M, Suginaka H, Usui T
Abstract excerpt
The growth rate of biofilm cells of a leucine-requiring mutant Pseudomonas aeruginosa HU1 was regulated by the leucine concentration in the chemically defined medium, and the effect of the growth rate of biofilm cells on the antimicrobial activities of the antimicrobial agents piperacillin (PIPC), imipenem (IPM) and ofloxacin (OFLX) were evaluated. PIPC showed little effect on the biofilm bacteria regardless of...
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