Article
Mutations in the c-erbA beta 1 gene: do they underlie euthyroid fibromyalgia?
Medical hypotheses - 1 Feb 1997
Lowe J C, Cullum M E, Graf L H, Yellin J
Abstract excerpt
Fibromyalgia, a chronic condition of widespread pain, stiffness, and fatigue, has proven unresponsive to drugs, the use of which is based on the 'serotonin-deficiency hypothesis'. An alternative hypothesis-failed transcription regulation by thyroid hormone-can explain the serotonin deficiency and other objective findings and symptoms of euthyroid fibromyalgia. Virtually every feature of fibromyalgia corresponds...
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