Article
Interferon-alpha 2b treatment in hepatitis B carriers. Effect on hepatitis B virus DNA levels in children infected with different genotypes.
Acta paediatrica (Oslo, Norway : 1992) - 1 Feb 1997
Sangfelt P, Norder H, Magnius L O, Alaeus A, Carlsson T, Reichard O
Abstract excerpt
Eleven hepatitis B virus (HBV) carrier children, infected with genotypes A-D, were treated with interferon-alpha. Two children had a sustained loss of hepatitis B e-antigen and HBV DNA. They were infected with the non-Asian genotypes A and D, and had low HBV DNA and high ALT levels in serum before treatment. However, HBV DNA titres decreased during treatment also in children infected with the East-Asian genotypes...
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