Human orosomucoid polymorphism: molecular basis of the three common ORM1 alleles, ORM1*F1, ORM1*F2, and ORM1*S.

doi:10.1007/s004390050378

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Article

Human orosomucoid polymorphism: molecular basis of the three common ORM1 alleles, ORM1F1, ORM1F2, and ORM1*S.

Human genetics - 1 Mar 1997

Yuasa I, Umetsu K, Vogt U, Nakamura H, Nanba E, Tamaki N, Irizawa Y

Abstract excerpt

The human orosomucoid (ORM) is controlled by two closely linked loci, ORM1 and ORM2, and two tandem genes, AGP1 and AGP2, encoding the proteins produced by the two loci, have been cloned. In this study the molecular basis of ORM1 polymorphism was investigated. For the detection of mutations the p...

Topics

Alleles
Animals
DNA Primers
Humans
Mutation
Orosomucoid
Polymerase Chain Reaction
Polymorphism, Genetic
Polymorphism, Restriction Fragment Length
Polymorphism, Single-Stranded Conformational

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