Cloning and characterization of the Bacteroides fragilis metalloprotease toxin gene.

doi:10.1128/IAI.65.3.1007-1013.1997

Back to search

Article

Cloning and characterization of the Bacteroides fragilis metalloprotease toxin gene.

Infection and immunity - 1 Mar 1997

Franco A A, Mundy L M, Trucksis M, Wu S, Kaper J B, Sears C L

Abstract excerpt

Strains of Bacteroides fragilis that produce a ca. 20-kDa heat-labile protein toxin (termed B. fragilis toxin [BFT]) have been associated with diarrheal disease of animals and humans. BFT alters the morphology of intestinal epithelial cells both in vitro and in vivo and stimulates secretion in li...

Topics

Amino Acid Sequence
Animals
Bacterial Toxins
Bacteroides fragilis
Base Sequence
Cloning, Molecular
Gene Dosage
Genes, Bacterial
Genetic Variation
Humans
Metalloendopeptidases
Molecular Sequence Data
Polymerase Chain Reaction
Swine

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.