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Article

Diversity of the Metalloprotease Toxin Produced by Enterotoxigenic Bacteroides fragilis

1 May 2002

Abstract excerpt

Enterotoxigenic Bacteroides fragilis (ETBF) strains produce a 20-kDa zinc metalloprotease toxin (BFT) associated with diarrheal disease of animals, young children, and adults. BFT stimulates secretion in intestinal loops in vivo and modifies epithelial cell morphology in vitro. The B. fragilis toxin (bft) gene from ETBF strain 86-5443-2-2 (piglet; bft-2) revealed significant nucleotide and predicted amino acid...

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Identifiers

PMID: 11953383
DOI: 10.1128/iai.70.5.2463-2471.2002

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