Article
Genetic, epigenetic, dysgenetic, and non-genetic mechanisms in tumorigenesis.
Critical reviews in oncogenesis - 1 Jan 1995
Simons J W
Abstract excerpt
A not yet understood phenomenon in carcinogenesis is the enormous difference in cancer susceptibility of cells from different species and of cells from individuals within the same species but with different age. Reviewing of the literature points to the promotion phase as the key for this difference. The essence of promotion appears to be a profound switch in the cell functions that enable cells to respond to...
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