Article
DNA testing in familial hypertrophic cardiomyopathy: clinical and laboratory implications.
Clinical genetics - 1 Oct 1996
Smart R V, Yu B, Le H, French J A, Richmond D R, Jeremy R W, Semsarian C, Cheung L, Ross D A, Trent R J
Abstract excerpt
Counselling and clinical assessment in familial hypertrophic cardiomyopathy (FHC) is difficult, particularly in the young, since echocardiographic and ECG changes may not be diagnostic and clinical severity can vary. From 1990, when the beta-cardiac myosin heavy chain gene was implicated in the a...
Topics
- Cardiomyopathy, Hypertrophic
- DNA
- Genetic Linkage
- Genetic Testing
- Humans
- Molecular Probe Techniques
- Mutation
- Myosin Heavy Chains
- Pedigree