Article
Thyroid Hormone-Responsive Genes in Developing Cerebellum Include a Novel Synaptotagmin and ahairlessHomolog
15 Dec 1996
Abstract excerpt
Proper development of the mammalian CNS requires sufficient thyroid hormone; thyroid hormone deficiency during a brief perinatal period produces severe neurological defects in humans and experimental animals. Thyroid hormone exerts its effects through nuclear receptors, which modulate the transcription of downstream genes in response to hormone binding. Surprisingly, few genes that are regulated by thyroid...
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