Article
Characterization of fhlA mutations resulting in ligand-independent transcriptional activation and ATP hydrolysis.
Journal of bacteriology - 1 Jan 1997
Korsa I, Böck A
Abstract excerpt
The FhlA protein belongs to the NtrC family of transcriptional regulators. It induces transcription from the -12/-24 promoters of the genes of the formate regulon by sigma54 RNA polymerase. FhlA is activated by binding of the ligand formate and does not require phosphorylation. A mutational analysis of the fhLA gene portion coding for the A and C domains was conducted with the aim of gaining information on the...
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