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Article

A neomutation of the thyroid-stimulating hormone receptor in a severe neonatal hyperthyroidism.

The Journal of clinical endocrinology and metabolism - 1 Jun 1996

de Roux N, Polak M, Couet J, Leger J, Czernichow P, Milgrom E, Misrahi M

Abstract excerpt

Until recently, neonatal hyperthyroidism has been considered to be related to the transplacental passage of thyroid-stimulating Ig present in the serum of the mother. We report here the case of a newborn who presented with severe hyperthyroidism, diffuse goiter, and important ocular signs (eyelid retraction and possibly proptosis). However, the absence of thyroid pathology in the parents and the lack of...

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Source

Identifiers

PMID: 8964822
DOI: 10.1210/jcem.81.6.8964822

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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