Article
Resumption of Meiosis is Initiated by the Accumulation of Cyclin B in Bovine Oocytes1
1 Dec 1996
Abstract excerpt
In mammals, oocytes are maintained at the G2/M border of the first meiotic division, often for years, before being ovulated. The oocytes wait for a signal that will trigger the chromosome segregation necessary to produce a haploid cell, which is required for fertilization. This event, meiotic resumption, is determined by activation of the M phase-promoting factor (MPF), constituted of the p34cdc2 kinase (p34) and...
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