Persistent hypokalemia due to a rare mutation in gitelman's syndrome.

Abstract excerpt

Chronic hypokalemia is the main finding in patients with Gitelman's syndrome (GS). GS, a variant of Bartter's syndrome, is an autosomal recessive renal disorder characterized by hypokalemia, hypomagnesemia, metabolic alkalosis, and hypocalciuria. GS is caused by inactivating mutations in the thiazide-sensitive sodium-chloride cotransporter gene. It is also called the "milder" form of Bartter's syndrome, as...

Topics

Join the communities discussing this publication.

• Gitelman Syndrome
• Hypokalemia
• Mutation
• Solute Carrier Family 12, Member 3