Article
Inhibition of estrogen-stimulated growth of uterine leiomyomas by selective estrogen receptor modulators.
Molecular carcinogenesis - 1 Nov 1996
Fuchs-Young R, Howe S, Hale L, Miles R, Walker C
Abstract excerpt
Uterine leiomyoma is the most frequent gynecologic neoplasm in women. By using a panel of cell lines derived from spontaneous Eker rat leiomyomas, we examined the estrogen-responsive phenotype of these tumor cells. Leiomyoma-derived ELT cell lines proliferated in response to estrogen, and estroge...
Topics
- Animals
- Cell Division
- Estradiol
- Estrogen Antagonists
- Female
- Fulvestrant
- Leiomyoma
- Phenotype
- Piperidines
- Raloxifene Hydrochloride
- Rats
- Receptors, Estrogen
- Tamoxifen
