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Article

Loss of growth polarity and mislocalization of septa in a Neurospora mutant altered in the regulatory subunit of cAMP-dependent protein kinase.

The EMBO journal - 1 Nov 1996

Bruno K S, Aramayo R, Minke P F, Metzenberg R L, Plamann M

Abstract excerpt

In filamentous fungi, growth polarity (i.e. hyphal extension) and formation of septa require polarized deposition of new cell wall material. To explore this process, we analyzed a conditional Neurospora crassa mutant, mcb, which showed a complete loss of growth polarity when incubated at the restrictive temperature. Cloning and DNA sequence analysis of the mcb gene revealed that it encodes a regulatory subunit of...

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PMID: 8918454
PMCID: PMC452324

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