Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Activation of mouse sperm T-type Ca <sup>2+</sup> channels by adhesion to the egg zona pellucida

12 Nov 1996

Abstract excerpt

The sperm acrosome reaction is a Ca(2+)-dependent exocytotic event that is triggered by adhesion to the mammalian egg's zona pellucida. Previous studies using ion-selective fluorescent probes suggested a role of voltage-sensitive Ca2+ channels in acrosome reactions. Here, wholecell patch clamp techniques are used to demonstrate the expression of functional T-type Ca2+ channels during mouse spermatogenesis. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ion channel regulation and function
Share to Reproductive Biology and Fertility
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 8917534
DOI: 10.1073/pnas.93.23.13004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Activation of mouse sperm T-type Ca <sup>2+</sup> channels by adhesion to the egg zona pellucidaPMID 8917534Read ↗

Ca<sup>2+</sup>Entry through Store-operated Channels in Mouse Sperm Is Initiated by Egg ZP3 and Drives the Acrosome ReactionSemantic proximity Read ↗

Control of the low voltage-activated calcium channel of mouse sperm by egg ZP3 and by membrane hyperpolarization during capacitationSemantic proximity Read ↗

Egg Coat Proteins Activate Calcium Entry into Mouse Sperm via CATSPER Channels1Semantic proximity Read ↗

Expression and differential cell distribution of low‐threshold Ca<sup>2+</sup> channels in mammalian male germ cells and spermSemantic proximity Read ↗

CaV3.2 T-type channels mediate Ca2+ entry during oocyte maturation and following fertilizationSemantic proximity Read ↗

ZP3-dependent activation of sperm cation channels regulates acrosomal secretion during mammalian fertilization.Semantic proximity Read ↗

Early ionic events in activation of the mammalian eggSemantic proximity Read ↗

Rediscovering sperm ion channels with the patch-clamp techniqueSemantic proximity Read ↗

Human spermatozoa possess a calcium‐dependent chloride channel that may participate in the acrosomal reactionSemantic proximity Read ↗

Transient exposure to calcium ionophore enables in vitro fertilization in sterile mouse modelsSemantic proximity Read ↗

Acrosome reaction: relevance of zona pellucida glycoproteinsSemantic proximity Read ↗

Expression, localization and functions in acrosome reaction and sperm motility of Ca(V)3.1 and Ca(V)3.2 channels in sperm cells: an evaluation from Ca(V)3.1 and Ca(V)3.2 deficient mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.