Article
The serotonin transporter is a potential susceptibility factor for bipolar affective disorder.
Neuroreport - 8 Jul 1996
Collier D A, Arranz M J, Sham P, Battersby S, Vallada H, Gill P, Aitchison K J, Sodhi M, Li T, Roberts G W, Smith B, Morton J, Murray R M, Smith D, Kirov G
Abstract excerpt
The serotonin transporter is a strong candidate for aetiological involvement in affective disorders and psychosis. We analysed a VNTR in intron 2 of the human serotonin transporter gene (hSERT) for allelic association with bipolar affective disorder, unipolar depression and schizophrenia. An increased frequency of allele 12 of the VNTR was observed in subjects with bipolar affective disorder (n = 191; chi 2 p =...
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