Article
Experimental reproduction of respiratory disease in calves with non‐cell‐culture‐passaged bovine respiratory syncytial virus
1 Sept 1996
Abstract excerpt
To reproduce experimentally clinical bovine respiratory syncytial virus (BRSV) infections in cattle, we isolated BRSV from a calf in the field that suffered from acute respiratory disease. Cell culture passage of the virus was avoided to prevent any modification of the biological properties of the virus. The isolated BRSV was passaged in specific-pathogen-free (SPF) calves. Lung lavage fluids of these calves,...
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